The National Institutes of Health this week awarded $31.5 million to establish three Centers for Accelerated Innovations, which will target technologies to improve patient care and advance public health. Hospital participants in the centers include Brigham and Women’s Hospital; Boston Children’s Hospital; Massachusetts General Hospital; Cleveland Clinic Lerner College of Medicine; and Cincinnati Children’s Hospital. Also this week, NIH awarded a consortium of medical and research centers $25 million to develop a database on clinically relevant genomic variants. As the researchers develop consensus on the clinical value of variants, professional organizations will use the information to develop clinical practice guidelines. Researchers at Brigham and Women's Hospital in Boston and Geisinger Health System in Danville, PA, are among the project participants.